Study of Thermal Degradation of PLGA, PLGA Nanospheres and PLGA/Maghemite Superparamagnetic Nanospheres
نویسندگان
چکیده
منابع مشابه
[Development of gene delivery system using PLGA nanospheres].
The development of nonviral vectors for the efficient and safe delivery to cells has long been awaited to facilitate gene therapy. Recently, many nonviral vectors modified with cationic lipids, cationic polymers, etc. have been reported. However, those nonviral vectors with cationic materials require improved stability, longer duration of gene expression, and reduced cytotoxicity. We successful...
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PURPOSE Itraconazole (ITZ) is a synthetic triazole antifungal agent, which is widely used for treatment and prevention of fungal infections. The purpose of this study is to develop ITZ-loaded poly(lactic-co-glycolic acid) (PLGA) nanospheres (PLGA-ITZ-NS) as a new sustained-release formulation for intravenous ITZ administration. MATERIALS AND METHODS PLGA-ITZ-NS were prepared by a nanoprecipit...
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Objective(s): The purpose of this study was preparation and evaluation of PLGA nanospheres containing the influenza virus and different adjuvants, Quillaja saponin (QS) and CpG-ODN. Materials and Methods: Nanospheres were prepared using the double emulsion-solvent evaporation method. The morphological and physicochemical properties were studied by scanning electron microscopy...
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lsd=20m SAXS and SANS study of PLGA nanospheres containing a Poloxamer shell C. Augsten1, A. Rübe1, M.A. Kiselev2, R. Gehrke3, J. Kohlbrecher4, K. Mäder1 1 University Halle-Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, 06120 Halle, Germany 2 Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, 141980 Dubna, Russia 3 HASYLAB (DESY), 22603 Hamburg, Germ...
متن کاملPLGA Nanospheres Loaded with Autoclaved Leishmania Major (ALM) and CpG-ODN: Preparation and in vitro Characterization
Objective(s) Several antigens, adjuvants and delivery systems have been evaluated for induction of protective immune responses against Leishmaniasis, but most of them have been inefficient. In this study, PLGA nanospheres as antigen delivery system CpG-ODN as an immunoadjuvant for increasing the immune responses against Autoclaved Leishmania major (ALM) were prepared and characterized. Materi...
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ژورنال
عنوان ژورنال: Materials Research
سال: 2015
ISSN: 1980-5373,1516-1439
DOI: 10.1590/1516-1439.045415